Efficiency of autofibroblasts in surgical treatment of parodontitis
- Autores: Grudyanov A.I1, Zorin V.L2, Pereverzev R.V1, Zorina A.I2, Bozo I.Y2,3
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Afiliações:
- Central Research Institute of Dentistry and maxillofacial surgery of MH Russia
- Human Stem Cells Institute
- A.I. Evdokimov Moscow State University of Medicine and Dentistry
- Edição: Volume 8, Nº 3 (2013)
- Páginas: 72-77
- Seção: Articles
- ##submission.dateSubmitted##: 05.01.2023
- ##submission.datePublished##: 15.10.2013
- URL: https://genescells.ru/2313-1829/article/view/120544
- DOI: https://doi.org/10.23868/gc120544
- ID: 120544
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Resumo
The destructive forms of periodontal disease have a high prevalence. Our study was aimed to evaluate the effectiveness of tissue-engineering osteoplastic material in treatment of patients with periodontal pathology. We have obtained autologous gingival fibroblasts of patients, combined with the hydroxyapatite carriage and transplanted on a standard surgical treatment of periodontitis destructive forms. As a control we used the material without cells implanted into periodontal defects of other affected teeth of the same patients. We have shown the better effect of tissue-engineering osteoplastic material regarding the periodontal pockets depth, but significant difference in bone regeneration and other indicators has not been revealed. Thus, a continuation of researches is required to modify the technology of tissueengineering osteoplastic material creation and to choice the more optimal carrier for gingival fibroblasts.
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Sobre autores
A. Grudyanov
Central Research Institute of Dentistry and maxillofacial surgery of MH RussiaMoscow
V. Zorin
Human Stem Cells InstituteMoscow
R. Pereverzev
Central Research Institute of Dentistry and maxillofacial surgery of MH RussiaMoscow
A. Zorina
Human Stem Cells InstituteMoscow
I. Bozo
Human Stem Cells Institute; A.I. Evdokimov Moscow State University of Medicine and DentistryMoscow
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