Efficacy and safety of mesenchymal stromal cells of bone marrow in patients with refractory forms Crohn's disease
- Authors: Knyazev O.V1, Parfenov A.I1, Shcherbakov P.L1, Ruchkina I.N1, Khomeriki S.G1, Konoplyannikov A.G2
-
Affiliations:
- Central Research Institute of Gastroenterology, Moscow
- Medical Radiological Research Center, Obninsk
- Issue: Vol 8, No 1 (2013)
- Pages: 76-84
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121624
- DOI: https://doi.org/10.23868/gc121624
- ID: 121624
Cite item
Abstract
Full Text
About the authors
O. V Knyazev
Central Research Institute of Gastroenterology, Moscow
A. I Parfenov
Central Research Institute of Gastroenterology, Moscow
P. L Shcherbakov
Central Research Institute of Gastroenterology, Moscow
I. N Ruchkina
Central Research Institute of Gastroenterology, Moscow
S. G Khomeriki
Central Research Institute of Gastroenterology, Moscow
A. G Konoplyannikov
Medical Radiological Research Center, Obninsk
References
- Crohn B.B., Ginzburg L., Oppenheimer G.D. Regional ileitis; a pathologic and clinical entity. J. Amer. Med. Assoc. 1932; 99: 1323—9.
- Белоусова Е.А. Реальные и потенциальные возможности лечения рефрактерных форм воспалительных заболеваний кишечника. Рус. мед. журн. 2005; 2: 88—95.
- Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998; 115(1): 182—205.
- Malchow H., Ewe K., Brandes J.W. et al. European cooperative Crohn's disease study (ECCDS): results of drug treatment. Gastroenterology 1984; 86: 249—66.
- Summers R.W., Switz D.M., Sessions J.T. et al. National cooperative Crohn's disease study group: results of drug treatment. Gastroenterology 1979; 77: 847—69.
- Faubion W.A., Loftus E.V., Harmsen W.S. et all. The natural history of corticosteroid therapy for inflammatory bowel disease: a population based study. Gastroenterology 2001; 121: 255—60.
- Breedveld F.C. Therapeutic monoclonal antibodies. Lancet 2000; 355: 735—40.
- Rutgeerts P., Feagan B.G., Lichtenstein G.R. et al. Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology 2004; 126: 402—13.
- Wayne G. Overview of stem cell therapy for Crohn's disease. Expert. Opin. Biol. Ther. 2009; 9(7): 841—7.
- Распоряжение Правительства РФ от 28.12.2012 №2580-р «Об утверждении Стратегии развития медицинской науки в РФ на период до 2025 года».
- Chapel A., Bertho J.M., Bensidhoum M. et al. Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome. J. Gene Med. 2003; 5: 1028—38.
- Krampera M., Glennie S., Dyson J. et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003; 101: 3722—29.
- Uccelli A., Pistoia V., Moretta L. Mesenchymal stem cells: a new strategy for immunosuppression? Trends Immunol. 2007; 28: 219-26.
- Abdi R., Fiorina P., Adra C.N. et al. Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetes. Diabetes 2008; 57: 1759-67.
- Meisel R., Zibert A., Laryea M. et al. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indolamine 2,3-dioxygenase-mediated tryptophan degredation. Blood 2004; 103: 4619-21.
- Rabinovitch A., Suarez-Pinzon W.L. Role of cytokines in the pathogenesis of autoimmune diabetes mellitus. Rev. Endocr. Metab. Disord. 2003; 4(3): 291-9.
- Drakos P.E., Nagler A., Or R. Case of Crohn’s disease in bone marrow transplantation. Am. J. Hematol. 1993; 43: 157-8.
- Molendijk I., Duijvestein M., van der Meulen-de A.E. et al. Immunomodulatory effects of mesenchymal stromal cells in Crohn’s disease. J. Allergy 2012; 2012: 187408.
- Best W.R., Becktel J.M., Singleton J.W. et al. Development of a Crohn’s disease activity index. National Cooperative Crohn’s Disease Study. Gastroenterology 1976; 70(3): 439-40.
- Sandborn W.J, Feagan B.G, Hanauer S.B. et al. А review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn’s disease. Gastroenterology 2002; 122: 512-30.
- Цыб А.Ф., Коноплянников А.Г., Колесникова А.И. и др. Получение и использование в медицине клеточных культур из мезенхимальных стволовых клеток костного мозга человека. Вестник Российской Академии медицинских наук 2004; 59(9): 71- 6.
- Lalu M.M., McIntyre L., Pugliese C. et al. Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One 2012; 7(10): e47559.
- Oyama Y., Traynor A.E., Barr W. et al. Allogeneic stem cell transplantation for autoimmune diseases: nonmyeloablative conditioning regimens. Bone Marrow Transplant. 2003; 32 Suppl 1: S81-3.