Delivery of cord blood cells modified with adenoviral vectors expressing GDNF into the area of spinal cord injury stimulates recovery of motor function and supports a population of glial cells
- 作者: Mukhamedshina Y.O1,2, Shaymardanova G.F3, Salafutdinov I.I2, Rizvanov A.A2, Povysheva T.V1, Masgutova G.A1, Nigmetzyanova M.V1, Chelyshev Y.A1,2
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隶属关系:
- Kazan State Medical University
- Kazan [Volga region) Federal University
- Kazan Institute of Biochemistry and Biophysics of RAS
- 期: 卷 8, 编号 3 (2013)
- 页面: 129-132
- 栏目: Articles
- ##submission.dateSubmitted##: 05.01.2023
- ##submission.datePublished##: 15.10.2013
- URL: https://genescells.ru/2313-1829/article/view/120626
- DOI: https://doi.org/10.23868/gc120626
- ID: 120626
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作者简介
Y. Mukhamedshina
Kazan State Medical University; Kazan [Volga region) Federal UniversityKazan
G. Shaymardanova
Kazan Institute of Biochemistry and Biophysics of RASKazan
I. Salafutdinov
Kazan [Volga region) Federal UniversityKazan
A. Rizvanov
Kazan [Volga region) Federal UniversityKazan
T. Povysheva
Kazan State Medical UniversityKazan
G. Masgutova
Kazan State Medical UniversityKazan
M. Nigmetzyanova
Kazan State Medical UniversityKazan
Yu. Chelyshev
Kazan State Medical University; Kazan [Volga region) Federal UniversityKazan
参考
- Gray S.J., Choi V.W., Asokan A. et al. Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration. Curr. Protoc. Neurosci. 2011; 4(17): 1-36.
- Tang X.Q., Wang Y., Huang Z.H. et al. Adenovirus-mediated delivery of GDNF ameliorates corticospinal neuronal atrophy and motor function deficits in rats with spinal cord injury. Neuroreport 2004; 15(3): 425-29.
- Degeorge M.L., Marlowe D., Werner E. et al. Combining glial cell line-derived neurotrophic factor gene delivery (AdGDNF) with L-arginine decreases contusion size but not behavioral deficits after traumatic brain injury. Brain Res. 2011; 27(1403): 45-56.
- Cheng H., Wu J.P., Tzeng S.F. Neuroprotection of glial cell line-derived neurotrophic factor in damaged spinal cords following contusive injury. J. Neurosci. Res. 2002; 69(3): 397-405.
- Mills C.D. Allchorne A.J., Griffin R.S. et al. GDNF selectively promotes regeneration of injury - primed sensory neurons in the lesioned spinal cord. Mol. Cell Neurosci. 2007; 36(2): 185-94.
- Park D.H., Lee J.H., Borlongan C.V. et al. Transplantation of umbilical cord blood stem cells for treating spinal cord injury. Stem Cell Rev. 2011; 7: 181-94.
- Chen C.T., Foo N.H., Liu W.S. et al. Infusion of human umbilical cord blood cells ameliorates hind limb dysfunction in experimental spinal
- Шаймарданова Г.Ф., Мухамедшина Я.О., Архипова С.С. и др. Посттравматические изменения спинного мозга крысы при трансплантации мононуклеарных клеток крови пуповины человека, модифицированных генами VEGF и FGF. Ж. Морфология 2011; 140(6): 36-42.
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- Basso D.M., Beattie M.S., Bresnahan J.C. A sensitive and reliable locomotor rating scale for open field testing in rats. Neurotrauma 1995; 12(1): 1-21.
- Lepore A. C., O'Donnell J., Kim A.S. et al. Reduction in expression of the astrocyte glutamate transporter, GLT1, worsens functional and histological outcomes following traumatic spinal cord injury. Glia 2011; 59(12): 1996-2005.
- Watzlawik J.O., Warrington A.E., Rodriguez M. PDGF is required for remyelination-promoting IgM stimulation of oligodendrocyte progenitor cell proliferation. PLoS One 2013; 8(2): 1-16.
- Baracskay K.L., Kidd G.J., Miller R.H. et al. NG2-positive cells generate A2B5-positive oligodendrocyte precursor cells. Glia 2007; 55: 1001-10.
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