Современный взгляд на потенциал регенеративных продуктов жировой ткани в лечении патологий кожных покровов

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Аннотация

На данном этапе развития регенеративной медицины жировая ткань как источник стволовых клеток является вариантом выбора ввиду её доступности, достаточного количества клеток и наиболее безболезненной процедуры забора материала. Высокий интерес к применению данного продукта в лечении рубцов, ран и других дерматологических заболеваний обусловлен продемонстрированными положительными результатами в других областях медицины.

В обзоре представлены данные об эффективности и безопасности использования клеточных и бесклеточных продуктов жировой ткани в лечении различных патологий кожных покровов. Использовали открытые электронные базы данных научной литературы PubMed (MEDLINE), Clinical Trials, eLIBRARY.RU. Поиск данных литературы проведён по следующим ключевым словам: «регенеративная медицина», «стромально-васкулярная фракция», «рубец», «кожа», «дерматология», «наножир», «стволовые клетки жировой ткани», «экзосомы», «липоаспират».

Показаны результаты использования регенеративных продуктов жировой ткани и обосновано их применение в лечении наиболее часто встречающихся и наиболее значимых заболеваний кожных покровов. Использование клеточных и бесклеточных продуктов жировой ткани в дерматологии и хирургии с целью улучшения качества кожных покровов — безопасное и перспективное направление. Для последующего эффективного применения методик необходимы дальнейшие исследования по оценке системного действия, а также разработка стандартизированных протоколов их использования.

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Анастасия Игоревна Гребень

Национальный медицинский исследовательский центр реабилитации и курортологии

Автор, ответственный за переписку.
Email: aik-nastya@mail.ru
ORCID iD: 0000-0002-2423-523X

младший научный сотрудник

Россия, Москва

Петр Серафимович Еремин

Национальный медицинский исследовательский центр реабилитации и курортологии

Email: ereminps@gmail.com
ORCID iD: 0000-0001-8832-8470
SPIN-код: 8597-6596

научный сотрудник

Россия, Москва

Елена Юрьевна Костромина

Национальный медицинский исследовательский центр реабилитации и курортологии

Email: bioimed07@hotmail.com
ORCID iD: 0000-0002-9728-7938

к.б.н., старший научный сотрудник

Россия, Москва

Павел Александрович Марков

Национальный медицинский исследовательский центр реабилитации и курортологии

Email: p.a.markov@mail.ru
ORCID iD: 0000-0002-4803-4803

к.б.н., старший научный сотрудник

Россия, Москва

Татьяна Николаевна Гребень

Национальный медицинский исследовательский центр реабилитации и курортологии

Email: greben72@inbox.ru
ORCID iD: 0000-0002-6001-0804

главный врач

Россия, Москва

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