Implant-Carrier of Cells Made of Porous Permeable Titanium
- Authors: Itin V.I.1, Pribytkov G.A.2, Khlusov I.A.2, Zagrebin L.V.3, Shestov S.S.3
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Affiliations:
- Structural Macrokynetic Department of Tomsk Scientific Senter (SD PAS)
- Institute of Physics Durability and Materialresearch
- Information-Cellular Medicine Center Lmd
- Issue: Vol 1, No 3 (2006)
- Pages: 59-63
- Section: Original Study Articles
- URL: https://genescells.ru/2313-1829/article/view/279626
- DOI: https://doi.org/10.23868/gc279626
- ID: 279626
Cite item
Abstract
The article presents the analysis of properties of a new material for implant production - porous titanium. It is demonstrated that the material possesses adequate mechanical characteristics. The absorption ofbiologic fluid was 7.5%. The material is compatible to living cells. While mouse bone marrow cells and fetal human hepatocytes were being cultured under Dextor system conditions and in vivo in mice such an implant functioned as a source of hemopoesis within the whole period of observation - up to 9 months. The data on depressing influence on growth and development of lymphomas were obtained. Thus, the material given can be considered as a perspective carrier for cells in transplantation and artificial organ creation.
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About the authors
V. I. Itin
Structural Macrokynetic Department of Tomsk Scientific Senter (SD PAS)
Author for correspondence.
Email: redaktor@celltranspl.ru
Russian Federation, Tomsk
G. A. Pribytkov
Institute of Physics Durability and Materialresearch
Email: redaktor@celltranspl.ru
Russian Federation, Tomsk
I. A. Khlusov
Institute of Physics Durability and Materialresearch
Email: redaktor@celltranspl.ru
Russian Federation, Tomsk
L. V. Zagrebin
Information-Cellular Medicine Center Lmd
Email: redaktor@celltranspl.ru
Russian Federation, Moscow
S. S. Shestov
Information-Cellular Medicine Center Lmd
Email: redaktor@celltranspl.ru
Russian Federation, Moscow
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