Morphologic changes within the brain of patients with dissimilated sclerosis undergone transplantation of autologous hematopoeitic stem cells

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About the authors

A. Efimenko

Author for correspondence.
Email: redaktor@celltranspl.ru
Russian Federation

References

  1. Bitsch A, Schuchardt J., Bunkowski S. et al. Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation. Brain 2000; 123(Pt 6): 1174-83.
  2. Blanco У., Saiz A., Carreras Е., Graus F. Autologous haematopoietic-stem- cell transplantation for multiple sclerosis. Lancet Neurol. 2005; 4(1): 54-63.
  3. Butovsky O., Тalpalar A.Е., Ben-Уaakov К., Schwartz М. Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs МНC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Мol. Cell. Neurosci. 2005; 29(3): 381-93.
  4. Chen J.Т., Collins О.L., Atkins Н.L. et al. Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis. Neurology 2006; 66(12): 1935-7.
  5. Inglese М., Мancardi G.L., Pagani Е. et al. Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation. J. Neurol. Neurosurg. Psychiatry 2004; 75(4): 643-4.
  6. Кuhlmann Т., Lingfeld G., Bitsch A. et al. Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time. Brain 2002; 125(Pt10): 2202-12.
  7. Openshaw Н., Lund B.Т., Кashyap A. et al. Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring. Biol. Blood Мarrow Тransplant. 2000; 6(5A): 563-75.

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