Clinical and experimental study on the use of combined cell transplant on the basis of multipotent mesenchymalstromal cells of adipose tissue in patients with severe deficiency of jaws bone tissue

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Abstract

The clinical and experimental study on the restoration of
bone tissue with tissue engineering scaffold based on stem
cells of adipose tissue and resorbable osteoplastic matrix. In a
pilot study proved the effectiveness of the transplant, founded
the dates of dental implantation. Use of tissue engineering
scaffold led to organotypic reconstruction of bone tissue in
the field of transplantation in patients with severe atrophy of
the alveolar process of the maxilla and mandible. As part of a
clinical trial were treated 20 patients.

About the authors

I S Alexeeva

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

A V Volkov

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

A A Kulakov

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

Central Research Institute of Dental and Maxillofacial Surgery, Moscow

D V Goldshtein

CJSC «ReMeTeks», MoscowMedical Genetics Research Center RAMS, Moscow

CJSC «ReMeTeks», MoscowMedical Genetics Research Center RAMS, Moscow

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