Post-traumatic reactions of a rat spinal cord after transplantation of human olfactory mucosa cells
- Authors: Shajmardanova GF1, Chelyshev J.A2, Lebedev SV3, Savchenko EA3, Viktorov IV3, Karasjov AV3, Chehonin VP3
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Affiliations:
- Kazan Institute of Biochemistry and Biophysics KSC RAS, Kazan
- Kazan State Medical University, Kazan3 Kazan (Volga region) Federal University, Kazan
- V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
- Issue: Vol 7, No 2 (2012)
- Pages: 92-96
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121644
- DOI: https://doi.org/10.23868/gc121644
- ID: 121644
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Abstract
level effect of the immediate transplantation of the human
olfactory mucosa cell into the damaged area were studied.
No immunosuppression was used. It was shown that
transplanted cells were survived as long as 7 days after
transplantation and located in rostral and caudal directions in
white matter on the 2 mm distance from points of injections.
It was shown also that transplanted cells migrated into
peripheral zone of the damaged area. The size of damaged
area in white and especially in gray matters were decreased
after 30 and 60 days after transplantation. The same time
after 30 days after transplantation the size of pathological
cavities mostly in anterior column were obviously diminished
and that number of undamaged myelinated nerve fibers were
increased in number around the area of transplantation
About the authors
G F Shajmardanova
Kazan Institute of Biochemistry and Biophysics KSC RAS, KazanKazan Institute of Biochemistry and Biophysics KSC RAS, Kazan
Ju A Chelyshev
Kazan State Medical University, Kazan3 Kazan (Volga region) Federal University, KazanKazan State Medical University, Kazan3 Kazan (Volga region) Federal University, Kazan
S V Lebedev
V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, MoscowV.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
E A Savchenko
V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, MoscowV.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
I V Viktorov
V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, MoscowV.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
A V Karasjov
V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, MoscowV.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
V P Chehonin
V.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, MoscowV.P. Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow
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