Allogennaya transplantatsiya kletok pupovinnoy krovi u bol'nykh s nekhodzhkinskimi limfomami
- Authors: Novitskiy AV1, Fominykh MS1
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Affiliations:
- Issue: Vol 6, No 1 (2011)
- Pages: 31-35
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121537
- DOI: https://doi.org/10.23868/gc121537
Cite item
Abstract
Высокодозная химиотерапия с последующей аллогенной трансплантацией гемопоэтических стволовых клеток (ГСК) является наиболее эффективным методом лечения у взрослых онкогематологических больных с высоким риском, однако, только треть из них имеет родственных доноров. Одним из альтернативных источников аллогенных ГСК в настоящее время стали клетки пуповинной крови. Использование клеток пуповинной крови применимо для лечения взрослых больных с резистентными формами высокоагрессивных лимфом, которым уже была выполнена аутогенная трансплантация периферических стволовых кроветворных клеток, в случае отсутствия потенциального подходящего по HLA донора.
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