A specific blocker of microRNA processing involved in cell differentiation processes has been discovered
- Authors: Grigoryan A.S.
- Issue: Vol 3, No 3 (2008)
- Pages: 15-16
- Section: Cell technology
- URL: https://genescells.ru/2313-1829/article/view/125022
- ID: 125022
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References
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In differentiated cells (right), let-7 pri-miRNA undergoes processing, resulting in the formation of mature Let-7 micro-RNA, which inhibits the expression of target genes at the post-transcriptional level. In undifferentiated embryonic cells (left), LLin28 binds Let-7 pri-miRNA and interferes with its processing
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