Experimental models for the treatment of diseases with unclear or predominantly autoimmune pathogenesis

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Abstract

The review is devoted to the search for new [non-hematopoietic] stem and progenitor cell populations of human umbilical cord blood, the possibilities of their isolation and therapeutic use. For convenience, the review is divided into several chapters, at the end of each of which there is a separate list of references.

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About the authors

A. V. Bersenev

Thomas Jefferson University

Author for correspondence.
Email: redaktor@celltranspl.ru
United States, Philadelphia

References

  1. Ende N.. Chen R., Mack R. NOD/LtJ type 1 diabetes in mice and the effect of stem cells [Berashis) derived from human umbilical cord blood. J. Med. 2002; 33: 181-7.
  2. Ende N.. Chen R., Redd! A.S. Transplantation of human umbilical cord blood cells improves glycemia and glomerular hypertrophy in type 2 diabetic mice. Biochem. Biophys. Res. Commun. 2004; 321:168-71.
  3. Ende N.. Chen R., Reddi A.S. Effect of human umbilical cord blood cells on glycemia and insulitis in type 1 diabetic mice. Biochem. Biophys. Res. Commun. 2004; 325: 665-9.
  4. Ende N.. Weinstein F., Chen R., Ende M. Human umbilical cord blood effect on sod mice [amyotrophic lateral sclerosis). Life Soi. 2000; 67[1): 53-9.
  5. Chen R., Ende N. The potential for the use of mononuclear cells from human umbilical cord blood in the treatment of amyotrophic lateral sclerosis in SOD-1 mice. J. Med. 2000; 31: 21-30.
  6. Garbuzova-Davis S., Willing A.E., Zigova T. et al. Intravenous administration of human umbilical cord blood cells in a mouse model of amyotrophic lateral sclerosis: distribution, migration, and differentiation. J. Hematother. Stem Cell Res. 2003;12:255-70.
  7. Ende N.. Czarneski J., Raveche E. Effect of human cord blood transfer on survival and disease activity in MRL-Lpr/Lpr mice. Clin. Immunol. Immunopath. 1995;75:190-5.
  8. Soria B., Roche E., Berna G. et al. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes. 2000; 49[2): 157-62.

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