DEVELOPMENT OF TDPI INHIBITORS BASED ON DERIVATIVES OF CHROMENE AS POTENTIAL ANTI-CANCER DRUGS
- Autores: Chepanova A.A1, Li-Zhulanov N.S2,3, Kurgina T.A1, Zakharenko A.L1, Zakharova O.D1, Volcho K.P2,3, Salakhutdinov N.F2,3, Lavrik O.I1,3
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Afiliações:
- Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRAS
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SBRAS
- Novosibirsk State University
- Edição: Volume 15, Nº 3S (2020)
- Páginas: 68-69
- Seção: Articles
- ##submission.dateSubmitted##: 17.01.2023
- ##submission.datePublished##: 15.12.2020
- URL: https://genescells.ru/2313-1829/article/view/122713
- DOI: https://doi.org/10.23868/gc122713
- ID: 122713
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Sobre autores
A. Chepanova
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRAS
Email: arinachepanova@mail.ru
Russian Federation, Novosibirsk
N. Li-Zhulanov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SBRAS; Novosibirsk State UniversityRussian Federation, Novosibirsk
T. Kurgina
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRASRussian Federation, Novosibirsk
A. Zakharenko
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRASRussian Federation, Novosibirsk
O. Zakharova
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRASRussian Federation, Novosibirsk
K. Volcho
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SBRAS; Novosibirsk State UniversityRussian Federation, Novosibirsk
N. Salakhutdinov
N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, SBRAS; Novosibirsk State UniversityRussian Federation, Novosibirsk
O. Lavrik
Novosibirsk Institute of Chemical Biology and Fundamental Medicine, SBRAS; Novosibirsk State UniversityRussian Federation, Novosibirsk
Bibliografia
- Interthal H et al., The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily. Proc Natl Acad Sci U S A. 2001;98(21):12009-14.
- Kamaletdinova T et al., The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers. Cells. 2019; 8(12),1625;
- Li-Zhulanov et al., A Novel Class of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Contains the Octahydro-2H-chromen-4-ol Scaffold. Molecules, 2018, 23(10), 2468;
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