THE PLASMINOGEN ACTIVATING SYSTEM AND NEUROLOGICAL REPAIR AFTER STROKE

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Emory University

Email: myepes@emory.edu
Department of Neurology and Center for Neurodegenerative Disease, School of Medicine and Veterans Affairs Medical Center

Merino P, Diaz A, Jeanneret V, Wu F, Torre E, Cheng L, Yepes M. Urokinase-type Plasminogen Activator (uPA) Binding to the uPA Receptor (uPAR) Promotes Axonal Regeneration in the Central Nervous System. J Biol Chem. 2017 Feb 17;292(7):2741-2753.
Wu F, Catano M, Echeverry R, Torre E, Haile WB, An J, Chen C, Cheng L, Nicholson A, Tong FC, Park J, Yepes M. Urokinase-type plasminogen Activator Promotes Dendritic Spine Recovery and Improves Neurological Outcome Following an Ischemic Stroke. J Neurosci. 2014 Oct 22;34(43):14219-32.
Jeanneret V, Wu F, Merino P, Torre E, Diaz A, Cheng L, Yepes M. Tissue-Type Plasminogen Activator Modulates the Postsynaptic Response of Cerebral Cortical Neurons to the Presynaptic Release of Glutamate.Front Mol Neurosci. 2016 Nov 9;9:121.
Jeanneret V, Yepes M. Tissue-type plasminogen activator is a regulator of synaptic function in the central nervous system. Neural Regen Res. 2017 Mar;12(3):362-365.
Jeanneret V, Yepes M. The Plasminogen Activation System Promotes Dendritic Spine Recovery and Improvement in Neurological Function After an Ischemic Stroke. Transl Stroke Res. 2016 Feb 4. [Epub ahead of print]
Yepes M. Tissue- Type Plasminogen Activator is a Neuroprotectant in the Central Nervous System.Front Cell Neurosci. 2015 Aug 17;9:304.

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