Effect of Nonspecific Inhibitors of DNA Methyltransferase and Histone Deacetylase on the Efficiency of Reprogramming of Mouse Embryonic Fibroblasts

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Okita К., Ichisaka Т., Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007; 448: 313-317.
Мaherali N., Sridharan R., Xie W. et al. Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell 2007; 1: 55-70.
Тakahashi К., Тanabe К., Ohnuki М. et al. Induction of Pluripotent Stem Cells from Adult Нuman Fibroblasts y Defined Factors. Cell 2007; 131: 861-872.
Park I.Н., Zhao R., West J.A. et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 2008; 451: 141-146.
Blelloch ., Wang Z., Мeissner A. et al. Reprogramming efficiency following somatic cell nuclear transfer is influenced y the differentiation and methylation state of the donor nucleus. Stem ells 2006; 24 2007-13.
Nakagawa М., Yoyanagi М., Тanabe К. et al. Generation of induced pluripotent stem cells without Мyc from mouse and human fibroblasts. Nat. Biotechnol. 2008; 26: 101-106.

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