Pluripotent hematopoietic stem cells and expression of myeloid markers - search for the site of leukemic transformation

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Email: redaktor@celltranspl.ru
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Passegue Е., Jamieson С.Н., Ailles L.E., Weissman I.L. Normal and leukemic hematopoiesis: areleukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc. Natl. Acad. Sol. USA 2003; 100[Suppl. 1): 11842-9.
Warner J.K., Wang J.C., Hope K.J. et al. Concepts of human leukemic development. Oncogene 2004; 23: 7164-77.
LapidotT., Sirard C., Vormoor J. et al. A cell initiating human acute myeloid leukemia after transplantation into SCID mice. Nature 1994; 367: 645-8.
Bonnet D„ Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat. Med. 1997; 3: 730-7.
Satoh C., Ogata K. Hypothesis: Myeloid-restricted hematopoietic stem cells with self-renewal capacity may be the transformation site in acute myeloid leukemia. Leuk. Res. 2005; Epub.
Hu M„ Krause D„ Greaves M. et al. Multilineage gene expression precedes commitment in the hemopoietic system. Genes Dev. 1997; 11: 774-85.
Orkin S.H. Priming the hematopoietic pump. Immunity 2003; 19: 633-4.
Sudo K., Ema H., Morita Y., Nakauchi H. Age-associated characteristics of murine hematopoietic stem cells. J. Exp. Med. 2000; 192:1273-80.

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