THE ROLE OF THE INTERACTION BETWEEN PROTEINKINASE C-ABL AND PROTEIN P53 IN THE REGULATION OF ACTIVATION OF THE ERK1/2 CASCADE
- Authors: Oleinik E.A1, Naumova A.A1, Glazova M.V1
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Affiliations:
- Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences
- Issue: Vol 15, No 3S (2020)
- Pages: 170-171
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/123222
- DOI: https://doi.org/10.23868/gc123222
- ID: 123222
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About the authors
E. A Oleinik
Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of Sciences
Email: ekaterina.oleynik96@mail.ru
St-Petersburg, Russia
A. A Naumova
Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of SciencesSt-Petersburg, Russia
M. V Glazova
Sechenov Institute of Evolutionary Physiology and Biochemistry Russian Academy of SciencesSt-Petersburg, Russia
References
- Zosen, D. V., & Glazova, М. V. (2014). Role p53 and MAPK signaling integration in the regulation of PC12 cell neural differentiation. Ross Fiziol Zh Im IM Sechenova, 100(12), 1431-1442.
- Levav-Cohen, Y., Goldberg, Z., Zuckerman, V., Grossman, T., Haupt, S., & Haupt, Y. (2005). C-Abl as a modulator of p53. Biochem Biophys Res Commun, 331(3), 737-749. doi: 10.1016/j.bbrc.2005.03.152
- Brown A, Browes C., Mitchell M., Montano X. c-abl is involved in the association of p53 and trk A. Oncogene. 19 (26): 3032-40. 2000.
- Long J., Liao G., Yinna Wang Y, Tang D.D. Specific protein 1, c-Abl and ERK1/2 form a regulatory loop. J. Cell Science. 132. doi: 10.1242/jcs.222380. 2019.
- Lee S.W., Fang L., Igarashi M., Ouchi T., Lu K.P., Aaronson S.A. Sustained activation of Ras/Raf/mitogen-activated protein kinase cascade by the tumor suppressor p53. Proc Natl Acad Sci U S A. 97 (15): 8302-5. 2000.
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