MEMBRANE ACTIVITY OF VIRAL FUSION INHIBITORS OF PERYLENE SERIES



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About the authors

E. V Shekunov

Institute of Cytology RAS

Email: egor_shekunov@mail.ru
Saint-Petersburg, Russia

S. S Efimova

Institute of Cytology RAS

Saint-Petersburg, Russia

A. A Chistov

Shemyakin-Ovchinnikov Institute of Bioorganic chemistry; National Research University Higher School of Economics

V. A Korshun

Shemyakin-Ovchinnikov Institute of Bioorganic chemistry; National Research University Higher School of Economics

A. V Ustinov

Shemyakin-Ovchinnikov Institute of Bioorganic chemistry; National Research University Higher School of Economics

O. S Ostroumova

Institute of Cytology RAS

Saint-Petersburg, Russia

References

  1. Vigant F., Lee J., Hollmann A. et al. A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion. PLoS pathogens. 2013; 9(4).
  2. Chistov A. A., Orlov A. A., Streshnev P. P. et al. Compounds based on 5-(perylen-3-ylethynyl) uracil scaffold: High activity against tick-borne encephalitis virus and non-specific activity against enterovirus A. European journal of medicinal chemistry. 2019; 171: 93-103.
  3. Gerl M. J., Sampaio J. L., Urban S. et al. Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane. Journal of Cell Biology. 2012; 196(2): 213-221.
  4. Ivanova P. T., Myers D. S., Milne S. B. et al. Lipid Composition of the Viral Envelope of Three Strains of Influenza Virus - Not All Viruses Are Created Equal. ACS infectious diseases. 2015; 1(9): 435-442.

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