Antitumor cytostatic doxorubicin in liposomal form does not have a damaging effect on mitochondria



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About the authors

E. R Nikitina

Sechenov Institute of evolutionary physiology and biochemistry RAS

Email: elena.nikitina@bk.ru
St. Petersburg, Russia

S. M Korotkov

Sechenov Institute of evolutionary physiology and biochemistry RAS

St. Petersburg, Russia

S. G Petunov

Sechenov Institute of evolutionary physiology and biochemistry RAS

St. Petersburg, Russia

K. A Vasileva

Sechenov Institute of evolutionary physiology and biochemistry RAS

St. Petersburg, Russia

I. V Mindukshev

Sechenov Institute of evolutionary physiology and biochemistry RAS

St. Petersburg, Russia

A. I Krivchenko

Sechenov Institute of evolutionary physiology and biochemistry RAS

St. Petersburg, Russia

References

  1. Forrancs V.J. Overview of cardiac pathology in relation to anthracydine cardiac toxicity. Canc. Treat. Rep. 1978; 62: 955-61.
  2. Olson R.D., Mushlin P.S., Brenner D.E. et al. Doxorubicin cardio-toxicity may be caused by its metabolite, doxorubicinol. PNAS USA 1988; 85(10): 3585-9.
  3. Harrington K.L., Lewanski C.R., Stewart S.W. Liposomes as vehicles for targeted therapy of cancer. Part 2: Clinical development. Clin. Oncol. 2000; 12: 16-24.

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