From organ transplantation to reparative spheroids and «microtissues» in suspension 3D-culture

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Abstract

4 experimental alternatives has been developed for
organ transplantation: 1. Cell therapy as a suspension of
disorganized somatic and stem cells. 2. The Grafts of well
differentiated cells on 3D-matrix to compensate (restore)
the damaged function. 3. Translational medicine - single
selected pilot project of personalized medicine of auto- stem
cell sphere transplantation with a new emergent potential for
tissue morphogenesis and regeneration. 4. High throughput
cellular serial fabrics for multiple generation of standard
micro-tissues and 3D-mini-tissues. They are especially
devoted to this essay.

About the authors

V S Repin

Institute of General Pathology and Pathophysiology RAMS, Moscow

Institute of General Pathology and Pathophysiology RAMS, Moscow

I N Saburina

Institute of General Pathology and Pathophysiology RAMS, Moscow

Institute of General Pathology and Pathophysiology RAMS, Moscow

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