Isolation, culture and differentiation of rat (Rattus norvegicus) and hamster (Mesocricetus auratus)adipose derived multipotent mesenchymal stromal cells
- Authors: Katina MN1, Gaifullina RF1, Hayatova ZG2, Emene C.C.1, Rizvanov AA1
-
Affiliations:
- Kazan (Volga Region) Federal University, Kazan
- Kazan State Medical University, Kazan
- Issue: Vol 7, No 3 (2012)
- Pages: 82-87
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121597
- DOI: https://doi.org/10.23868/gc121597
- ID: 121597
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Abstract
perspective fields in modern medicine. Adipose derived
autological stem cells can be obtained for therapeutic
purposes. Animal model of human diseases are essential for
cell therapy research. However, the most frequently used
laboratory animals, such as rats and mice, cant suffer the
whole rate of common diseases of modern society. At the
same time Syrian hamsters can provide scientists with an
appropriate animal models of these diseases. Nevertheless,
we couldnt find any data on hamsters stem cells isolation
and their characteristics. In this study we first isolated Syrian
hamsters adipose derived stem cells, characterized their
morphology, features and differential potential in several
ways. These cells are much alike multipotent mesenchymal
stromal cells and can go through osteogenic and, adipogenic
differentiation. We have also shown that these cells can
differentiate in neurogenic way.
About the authors
M N Katina
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
R F Gaifullina
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
Z G Hayatova
Kazan State Medical University, KazanKazan State Medical University, Kazan
Ch Ch Emene
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
A A Rizvanov
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
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