The First experience of quantitative evaluation of therapeutic angiogenesis results
- Authors: Katelnitskiy I.I1, Katelnitskiy I.L1, Alexeeva G.A1
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Affiliations:
- Rostov State Medical University, Rostov-on-Don
- Issue: Vol 7, No 4 (2012)
- Pages: 83-85
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121582
- DOI: https://doi.org/10.23868/gc121582
- ID: 121582
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Abstract
The goal of research is objective evaluation of effectiveness of therapeutic angiogenesis in patients with critical lower limb ischemia of the atherosclerotic etiology. It was shown that angiogenesis induction by drug Neovasculgen was manifested by good clinical effect in the nearest period and that was confirmed by growth of tissue blood flow according to laser Doppler flowmetry. Use of technetium-pertehnetate- macroaggregates angioscintigraphy with intra-arterial administration of the drug allowed to assess objectively the increase of blood flow to the increased volume of the vascular bed.
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About the authors
I. I Katelnitskiy
Rostov State Medical University, Rostov-on-Don
IG. L Katelnitskiy
Rostov State Medical University, Rostov-on-Don
G. A Alexeeva
Rostov State Medical University, Rostov-on-Don
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