Polymer-stabilised magnetic nanoparticles do not affect the viability of magnetically-functionalised cells
- Authors: Dzamukova MR1, Naumenko EA1, Zakirova EY2, Dzamukov RA3, Shilyagin PA4, Ilinskaya ON1, Fakhrullin RF1
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Affiliations:
- Кazan (Volga region) Federal University, Kazan
- Federal Center of Toxicological, Radiological and Biological Safety, Kazan3 Republican
- Republican Clinical Hospital, Kazan
- Institute of Applied Physics RAS, Nizhny Novgorod
- Issue: Vol 7, No 3 (2012)
- Pages: 52-56
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121581
- DOI: https://doi.org/10.23868/gc121581
- ID: 121581
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Abstract
superparamagnetic iron oxide nanoparticles for the surface
modification of living cells. Magnetic functionalisation of cow
embryonic lung cells did not affect the viability of the coated
cells, confluent monolayer formation and proliferation, as
demonstrated using fluorescence and white light microscopy,
flow cytometry and MTT assay. Functionalised cells were
magnetically responsive. We believe that the single-step
approach described here is a novel and potentially promising
way to functionalise mammal cells with magnetic nanoparticles
for the subsequent applications in cell therapy, directed cells
delivery and spatial positioning in tissue engineering.
About the authors
M R Dzamukova
Кazan (Volga region) Federal University, KazanКazan (Volga region) Federal University, Kazan
E A Naumenko
Кazan (Volga region) Federal University, KazanКazan (Volga region) Federal University, Kazan
E Y Zakirova
Federal Center of Toxicological, Radiological and Biological Safety, Kazan3 RepublicanFederal Center of Toxicological, Radiological and Biological Safety, Kazan3 Republican
R A Dzamukov
Republican Clinical Hospital, KazanRepublican Clinical Hospital, Kazan
P A Shilyagin
Institute of Applied Physics RAS, Nizhny NovgorodInstitute of Applied Physics RAS, Nizhny Novgorod
O N Ilinskaya
Кazan (Volga region) Federal University, KazanКazan (Volga region) Federal University, Kazan
R F Fakhrullin
Кazan (Volga region) Federal University, KazanКazan (Volga region) Federal University, Kazan
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