Experience of preserved corneal transplantation for penetrating keratoplasty
- Authors: Taldaev R.E1, Andreeva D.I2, Kiassov A.P2
-
Affiliations:
- Republican Clinical Ophtalmology Clinic
- Kazan (Volga region) Federal University
- Issue: Vol 9, No 3 (2014)
- Pages: 136-139
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/120352
- DOI: https://doi.org/10.23868/gc120352
- ID: 120352
Cite item
Abstract
Corneal diseases are one of the leading causes of blindness and poor vision. Keratoplasty is the only effective method of treatment in case of corneal lesion or perforation. Since the use of the native cornea is restricted by the lifespan of the material and its limited availability, it is reasonable to use the preserved corneal transplants, especially in case of emergency. The analysis of 26 penetrating keratoplasties is adduced. One group of patients (22 eyes) were performed elective surgery, and the second group (4 eyes) - urgent intervention. Patients were follow-upped for 24 months. All patients were examined by standard methods, additionally; the amount of endothelial cell was counted. Transparent engraftment was achieved on 18 eyes (81%) in the first group and three eyes (75%) in the second group. Endothelial cell density was 1500±200/mm2. Visual acuity after surgery varies depending on the disease that caused keratoplasty, postoperative course, and the condition of posterior segment of the eye. Preserved cornea is a safe against blood transmitted infections, makes a penetrating keratoplasty possible in various diseases of the cornea, including the need for emergency surgery, and allows achieving a transparent and translucent engraftment in most cases.
Keywords
Full Text
About the authors
R. E Taldaev
Republican Clinical Ophtalmology Clinic
D. I Andreeva
Kazan (Volga region) Federal University
A. P Kiassov
Kazan (Volga region) Federal University
References
- West-Mays J.A., Dwivedi D.J. The keratocyte: corneal stromal cell with variable repair phenotypes. Int. J. Biochemistry & Cell Biology. 2006; 38: 1625-31.
- Wilson S.E., He Y.G., Weng J. et al. Epithelial injury induces keratocyte apoptosis: hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing. Exp. Eye Res. 1996; 62: 325-38.
- Funderburgh J.L. Keratan sulfate: structure, biosynthesis, and function. Glycobiology 2000; 10: 951-8.
- Kim W.J, Rabinowitz Y.S., Meisler D.M., Wilson S.E. Keratocyte apoptosis associated with keratoconus. Exp. Eye Res. 1999; 69(5): 475-81.
- Sundin O.H., Jun A.S., Broman K.W., Liu S.H. et al. Linkage of late-onset Fuchs corneal dystrophy to a novel locus at 13pTel-13q12.13. Invest. Ophthalmol. Vis. Sci. 2006; 47(1): 140-5.
- Полянская Н.К. Тактика лечения пациентов с язвами роговицы на фоне тяжелой соматической патологии. Клиническая офтальмология 2007; 8(1): 14-6.
- Мороз З.И., Тахчиди Х.П., Калинников Ю.Ю. и др. Современные аспекты кератопластики. Материалы всерос. науч.-практ. конф. «Федоровские чтения. Новые технологии в лечении заболеваний роговиц». Москва; 2004: 280-7.
- Копаева В. Г. Глазные болезни. М.: Медицина, 2002.