Differentiation of epitheliocytes of mesonephric and paramesonephric ducts in human embryogenesis

The aim of the research was to give the morphofunctional characteristics of embryonic histogenesis of the female genital tract abortuses. We have studied 50 abortuses at the age of 4-12 weeks of gestation. The fixation of material and of the sample preparations were carried out according to the principles of quantitative histochemistry. According to the data obtained, paramesonefric ducts are found in the composition of the urogenital blastema to which coelomic epithelium cells can migrate. Since in this time the more differentiated ducts are mesonefric and archinephron is the organ that carries out its function, it is undeniable that the development of paramesonefric ducts goes on vector of the cranio-caudal growth of mesonefric ducts. The formation of a common utero-vaginal canal occurs through the convergence of the paramesonefric duct walls. Herewith the septum between ducts is persisted. Epitheliocytes in the medial walls of the ducts are deformed, nuclei decrease in size. The shape of the nuclei changes and rectangular nuclei dominate. The cells which have a light nucleoplasm are detected, in other cells there is a piknotic nucleus in the center; there are cells with nuclei having the semilunar shape, cells with two fragments of the nucleus, one of which is dark and the other one is light; nucleus with cuspidal protrusions at one pole, cigar-shaped nucleus. The formation of the complex relationships between the paramesonefric ducts at the entrance into mesenchymal block allows to make a suggestion on the critical period of the female genital tract development.

embryonic histogenesis, paramesonephric duct, mesonephric duct