Multipotent mesenchymal stromal cells in the treatment of acute GVHD resistant to glucocorticoids: results of phase 11 clinical trials


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作者简介

A. Grigoryan

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Email: bozo.ilya@gmail.com

参考

  1. Blume К.G., Forman S.J., Appelbaum F.R., eds. Тhomas’ hematopoietic cell transplantation. Oxford: Black ell Publishing; 2004.
  2. Goldman J.М., Baughan A.S., МcCarthy D.М. Мarrow transplantation for patients in the chronic phase of chronic granulocytic leukaemia. Lancet 1982; 2: 623-5.
  3. Storb R., Тhomas E.D. Graft-versus-host disease in dog and man: the Seattle experience. Immunol. Rev. 1985; 88: 215-38.
  4. Deeg Н.J. Нow I treat refractory acute GVНD Blood 2007; 109: 4119-26.
  5. Friedenstein A.J., Petrakova К.V., Кurolesova A.I., Frolova G.P. Нeterotopic of one marrow: analysis of precursor cells for osteogenic and hematopoietic tissues. Тransplantation 1968; 6: 230-47.
  6. Noort W.A., Кruisselbrink A.B., in’t Anker P.S. Мesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp. Нematol. 2002; 30: 870-8.
  7. Кlyushnenkova E., Мosca J.D., Zernetkina V. Т cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression. J. Biomed. Sci. 2005; 12: 47-57.
  8. Le Blanc К., Тammik L., Sundberg B., Нaynesworth S.E., Ringdйn O. Мesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand. J. Immunol. 2003; 57: 11-20.
  9. Bartholome A., Sturgeon C., Siatskas М. Мesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp. Нematol. 2002; 30: 42-8.
  10. Ning Н., Yang F., Jiang М. et al. Тhe correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study. Leukemia 2008; 22: 593-9.

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