The combination of intestinal chelators for correction of environmentally caused by trace element imbalance in children at the cellular level



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Abstract

Normally, the human body maintains a certain balance of micronutrients. The danger of a constant inflow of toxic elements from the environment caused by the inability to selfdestruction and elimination from the body, so the search for an optimal balance correction of metals is carried out. By AAS definition of the nine most common toxic and essential trace elements in hair of children in all 11 children's clinics service areas was held: Pb, Cu, Zn, Cr, Sr, Mn, Ni, Fe, Cd. Six different types of biopolymer ehnterosorbents: pectin, alginates, chitosan, microcrystalline cellulose and chitin were studied in the proposed model. A method of produce and combination of biopolymer and mineral enterosorbents with qualitatively new properties and lower cost compared to monosorbents was developed. 11 most common toxic and essential trace elements in hair of children were analyzed. The most variable and requiring of geographically differentiated correction elements in areas of research were determined. The most effective biopolymer enterosorbents and their combinations with mineral enterosorbents were discovered. Experimentally a method of producing composite enterosorbents based colloids was created. The highest sorption capacity related to of Zn, Cd, Fe and Cu requiring geographically differentiated correction was noted in combination of octahedral smectite and chitosan tests.

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About the authors

J. A Tunakova

A.N. Tupolev Kazan State Technical University

R. I Fayzullin

Kazan (Volga region) Federal University

V. S Valiev

Institute for environment and mineral resources of the AS of the Republic of Tatarstan

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