Effects of Н2О2-plasma processing on properties of cellular scaffolds made of «Bioplastotan»resorbing polyesters
- Authors: Nikolaeva ED1, Goncharov DB2, Shishatskaya EI2
-
Affiliations:
- Institute of Biophysics, Siberian branch of the RAS, Krasnoyarsk
- Siberian Federal university, Krasnoyarsk
- Issue: Vol 6, No 2 (2011)
- Pages: 65-70
- Section: Articles
- Submitted: 11.01.2023
- Published: 15.06.2011
- URL: https://genescells.ru/2313-1829/article/view/121666
- DOI: https://doi.org/10.23868/gc121666
- ID: 121666
Cite item
Abstract
Produced from «Bioplastotan» resorbing polyesters (linear
polyesters of hydroxyl derivatives alkanoic acids) scaffolds for
cell culturing such as films, pressed 3-D forms and nonwoven
fabric from ultrathin fibers are characterized. Two types of
polymers - a homopolymer of the 3-hydroxybutyric acid and
a copolymer formed by monomers of the 3-hydroxybutyric
and 3-hydroxyvalerianic acids are studied. Surface properties
of developed polymer scaffolds, sterilized with autoclaving
and Н2О2-plasma processing are compared. It is shown that
plasma has beneficial effects resulting in decrease of the
watering contact angle and increase of surface hydrophilic
properties. Positive effects of Н2О2-plasma processing
of scaffold surface on culturing cell adhesion and viability
compared with autoclaving sterilization is demonstrated on
NIH 3T3 line fibroblast culturing.
polyesters of hydroxyl derivatives alkanoic acids) scaffolds for
cell culturing such as films, pressed 3-D forms and nonwoven
fabric from ultrathin fibers are characterized. Two types of
polymers - a homopolymer of the 3-hydroxybutyric acid and
a copolymer formed by monomers of the 3-hydroxybutyric
and 3-hydroxyvalerianic acids are studied. Surface properties
of developed polymer scaffolds, sterilized with autoclaving
and Н2О2-plasma processing are compared. It is shown that
plasma has beneficial effects resulting in decrease of the
watering contact angle and increase of surface hydrophilic
properties. Positive effects of Н2О2-plasma processing
of scaffold surface on culturing cell adhesion and viability
compared with autoclaving sterilization is demonstrated on
NIH 3T3 line fibroblast culturing.
About the authors
E D Nikolaeva
Institute of Biophysics, Siberian branch of the RAS, KrasnoyarskInstitute of Biophysics, Siberian branch of the RAS, Krasnoyarsk
D B Goncharov
Siberian Federal university, KrasnoyarskSiberian Federal university, Krasnoyarsk
E I Shishatskaya
Siberian Federal university, KrasnoyarskSiberian Federal university, Krasnoyarsk
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