CURRENT STATE OF TISSUE ENGINEERING FOR CARTILAGE REGENERATION



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Abstract

The development of biomedical cell products for damaged cartilage recovery is an important direction of regenerative medicine. The review examines the main issues related to biodegradable tissue scaffold and hydrogel properties: selection of appropriate biomaterials, cells loaded and other supplements that could provide the best conditions for cartilage recovery. The results of in vitro and in vivo studies, as well as clinical trials registered at the National Institutes of Health database (ClinicalTrials.gov), are considered.

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About the authors

E. E Beketov

A. Tsyb Medical Radiological Research Center, the branch of the National Medical Research Radiological Center

Email: beketov.ee@yandex.ru

E. V Isaeva

A. Tsyb Medical Radiological Research Center, the branch of the National Medical Research Radiological Center

P. V Shegay

National Medical Research Radiological Center of the Ministry of Health of the Russian Federation

S. A Ivanov

A. Tsyb Medical Radiological Research Center, the branch of the National Medical Research Radiological Center

A. D Kaprin

National Medical Research Radiological Center of the Ministry of Health of the Russian Federation

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