Perculiarities of physiologic and reparative osteogenesis following the transfusion of bone marrow mononuclear cells
- Authors: Deev R.V.1, Tsupkina N.V.2, Sergeev V.S.1, Serikov V.B.3, Gololobov V.G.1, Pinaev G.P.2
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Affiliations:
- Kirov Military Medical Academy
- RAS Institution of Cytology (Cellular Cultures Department)
- Children’s Hospital Oakland Research Institute
- Issue: Vol 1, No 3 (2006)
- Pages: 54-58
- Section: Original Study Articles
- URL: https://genescells.ru/2313-1829/article/view/279171
- DOI: https://doi.org/10.23868/gc279171
- ID: 279171
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Abstract
Physiologic and reparative regeneration of bone tissue after transfusion of bone marrow GFP-positive mononuclear cells of mice C57B1 /6-TgN(ACTbGFP)1 Osb was studied in C57B1/6 mice exposed to radiation. It is shown that transplanted cells are able to differentiate into osteoblasts and osteocytes in both physiologic and reparative osteogenesis, these cells having priority to proliferation and differentiation in the recipient exposed to radiation. The GFP-positive osteocytes number within the substance reached 31±8%.
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About the authors
R. V. Deev
Kirov Military Medical Academy
Author for correspondence.
Email: redaktor@celltranspl.ru
Russian Federation, Saint-Petersburg
N. V. Tsupkina
RAS Institution of Cytology (Cellular Cultures Department)
Email: redaktor@celltranspl.ru
Russian Federation, Saint-Petersburg
V. S. Sergeev
Kirov Military Medical Academy
Email: redaktor@celltranspl.ru
Russian Federation, Saint-Petersburg
V. B. Serikov
Children’s Hospital Oakland Research Institute
Email: redaktor@celltranspl.ru
United States, Oakland, CA 94609
V. G. Gololobov
Kirov Military Medical Academy
Email: redaktor@celltranspl.ru
Russian Federation, Saint-Petersburg
G. P. Pinaev
RAS Institution of Cytology (Cellular Cultures Department)
Email: redaktor@celltranspl.ru
Russian Federation, Saint-Petersburg
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