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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Genes &amp; Cells</journal-id><journal-title-group><journal-title xml:lang="en">Genes &amp; Cells</journal-title><trans-title-group xml:lang="ru"><trans-title>Гены и Клетки</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Genes and Cells</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-1829</issn><issn publication-format="electronic">2500-2562</issn><publisher><publisher-name xml:lang="en">Human Stem Cells Institute</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">279626</article-id><article-id pub-id-type="doi">10.23868/gc279626</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original Study Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Implant-Carrier of Cells Made of Porous Permeable Titanium</article-title><trans-title-group xml:lang="ru"><trans-title>Имплантат - носитель клеточного материала из пористого проницаемого титана</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Itin</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Итин</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pribytkov</surname><given-names>G. A.</given-names></name><name xml:lang="ru"><surname>Прибытков</surname><given-names>Г. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khlusov</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Хлусов</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zagrebin</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Загребин</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shestov</surname><given-names>S. S.</given-names></name><name xml:lang="ru"><surname>Шестов</surname><given-names>С. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Structural Macrokynetic Department of Tomsk Scientific Senter (SD PAS)</institution></aff><aff><institution xml:lang="ru">Отдел структурной макрокинетики Томского научного центра СО РАН</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Physics Durability and Materialresearch</institution></aff><aff><institution xml:lang="ru">Институт физики прочности и материаловедения СО РАН</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Information-Cellular Medicine Center Lmd</institution></aff><aff><institution xml:lang="ru">ООО «Центр информационно-клеточной медицины»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2006-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2006</year></pub-date><volume>1</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>59</fpage><lpage>63</lpage><history><date date-type="received" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-02-24"><day>24</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2006, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2006, Эко-Вектор</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://genescells.ru/2313-1829/article/view/279626">https://genescells.ru/2313-1829/article/view/279626</self-uri><abstract xml:lang="en"><p>The article presents the analysis of properties of a new material for implant production - porous titanium. It is demonstrated that the material possesses adequate mechanical characteristics. The absorption ofbiologic fluid was 7.5%. The material is compatible to living cells. While mouse bone marrow cells and fetal human hepatocytes were being cultured under Dextor system conditions and in vivo in mice such an implant functioned as a source of hemopoesis within the whole period of observation - up to 9 months. The data on depressing influence on growth and development of lymphomas were obtained. Thus, the material given can be considered as a perspective carrier for cells in transplantation and artificial organ creation.</p></abstract><trans-abstract xml:lang="ru"><p>В работе проведен анализ свойств нового материала для изготовления имплантатов — пористого титана. Показано, что материал обладает достаточными механическими свойствами. Поглощение биологической жидкости составляло 7,5%. Материал совместим с живыми клетками. При культивировании клеток костного мозга мыши и фетальных человеческих гепатоцитов в условиях дексторовской системы и in vivo у мышей, такой имплантат функционирует как очаг гемопоэза в течение всего срока наблюдений - до 9 мес. Получены данные о депрессирующем влиянии на рост и развитие лимфом. Таким образом, данный материал можно рассматривать как перспективный носитель для клеток в трансплантологии и создания «искусственных органов».</p></trans-abstract><kwd-group xml:lang="en"><kwd>porous titanium</kwd><kwd>cells culture</kwd><kwd>implant-carrier</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пористый титан</kwd><kwd>культура клеток</kwd><kwd>имплантат-носитель</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Vacanti J.P., Vacanti C.A., Langer R.S. Neomorphogenesis of cartilage in vivo from cell culture. WO 901 2603; A61F2/30; A61 L27/00; C12N5/ 00. Publication data: 1 990-11 -01. 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