Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute133725Cell technologyНовости клеточных технологийShort CommunicationEndothelial progenitor cells of the bone marrow are not involved in the processes of tumor angiogenesis and are not necessary for the growth of malignant neoplasms.Эндотелиальные клетки-предшественницы костного мозга не участвуют в процессах опухолевого ангиогенеза и не являются необходимыми для роста злокачественных новообразованийSergeevV. S.СергеевВ. С.bozo.ilya@gmail.comPlaksaI. L.ПлаксаИ. Л.bozo.ilya@gmail.com150920083319212501202325012023Copyright ©; 2008, Eco-VectorCopyright ©; 2008, Эко-Вектор2008Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/133725[Bergers G., Benjamin L. Тumorigenesis and the angiogenic switch. Nat. Rev. Cancer 2003; 3: 401-10.][Ellis L., Нicklin D. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat. Rev. Cancer 2008; 8: 579-91.][Gao D., Nolan D., Мellick A. et al. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science 2008; 319: 195-8.][Lyden D., Нattori К., Dias S. et al. Impaired recruitment of one-marrow-derived endothelial and hematopoietic precursor cells locks tumor angiogenesis and growth. Nat. Мed. 2001; 7: 1194-201.][Nolan D., Ciarrocchi A., Мellick A. et al. Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes Dev. 2007; 21: 1546-58.][Нattori К., Dias S., Нeissig B. et al. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis y recruitment of vasculogenic and hematopoietic stem cells. J. Exp. Мed. 2001; 193: 1005-14.][Zhang F., Нackett N., Lam G. et al. Green fluorescent protein selectively induces НSP70-mediated up-regulation of COX-2 expression in endothelial cells. Blood 2003; 102: 2115-21.][Perry S., Zhao Y., Nie L. et al. Id1, but not Id3, directs long-term repopulating hematopoietic stem-cell maintenance. Blood 2007; 110 (7): 2351-60.]