Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute12511910.23868/gc125119ReviewsНаучные обзорыReview ArticleDifferentiation of PC cells into hepatocytes and liver repopulationДифференцировка клеток ПК в гепатоциты и репопуляция печениBersenevA. V.БерсеневА. В.
United States
redaktor@celltranspl.ruThomas Jefferson UniversityУниверситет Томаса Джефферсонаru150120062006144461801202318012023Received:18012023Accepted:18012023Published:15012006Copyright ©; 2023, Eco-VectorCopyright ©; 2023, Эко-Вектор2023Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/125119

The review is devoted to the search for new [non-hematopoietic] stem and progenitor cell populations of human umbilical cord blood, the possibilities of their isolation and therapeutic use. For convenience, the review is divided into several chapters, at the end of each of which there is a separate list of references.

Обзор посвящен поиску новых [негемопоэтических] стволовых и прогениторных клеточных популяций пуповинной крови человека, возможностей их выделения и терапевтического применения. Для удобства обзор разбит на несколько глав, в конце каждой из которых приводится отдельный список литературы.

Beerheide W., von Mach М.А., Ringel M. et al. Downregulation of Ь2- microglobulin in human cord blood somatic stem cells after transplantation into livers of SCID-mice: an escape mechanism of stem cells. Biochem. Biophys. Res. Commun. 2002; 294:1052-63.Newsome P.N., Johannessen I., Boyle S. et al. Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion. Gastroenterol. 2003; 124[7): 1891-900.Ishikawa F. Transplanted human cord blood cells give rise to hepatocytes in engrafted mice. Ann. N-Y Acad. Sol. 2003; 996:174-85.Danet G.H., Luongo J.L., Butler G. et al. C1qRp defines a new human stem cell population with hematopoietic and hepatic potential. Proc. Nat. Acad. Sol. USA 2002; 99: 10441-5.Wang X., Ge S., McNamara G. et al. et al. Albumin-expressing hepatocytelike cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells. Blood 2003; 101[10): 4201-8.Kakinuma S., Tanaka Y., Chinzei R. et al. Human umbilical cord blood as a source of transplantable hepatic progenitor cells. Stem Cells 2003; 21[2): 217-27.Di Campli C., Piscaglia A.C. et al. A human umbilical cord stem cell rescue therapy in a murine model of toxic liver injury. Dig. Liver. Dis. 2004; 36[9): 603-13.Turrini P„ Monego G., Gonzalez J. et al. Human hepatocytes in mice receiving pre-immune injection with human cord blood cells. Biochem. Biophys. Res. Commun. 2005; 326: 66-73.Sharma A.D., Cantz T„ Richter R. et al. Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver. Am. J. Pathol. 2005; 167(2): 555-64.Nonome K., Li X.K., Takahara T. et al. Human umbilical cord blood-derived cells differentiate into hepatocyte-like cells in the Fas-mediated liver injury model. Am. J. Physiol. Gastrointest. Liver. Physiol. 2005; 289[6): G1091-9.Kashofer K., Siapati E.K., Bonnet D. In vivo formation of unstable heterokaryons following liver damage and HSC/Progenitor transplantation. Stem Cells. 2005;10; Epub.Tanabe Y., Tajima F., Nakamura Y. et al. Analyses to clarify rich fractions in hepatic progenitor cells from human umbilical cord blood and cell fusion. Biochem. Biophys. Res. Commun. 2004; 324[2): 711-8.Hong S.H., Gang E.J., Jeong J.A. et al. In vitro differentiation of human umbilical cord blood-derived mesenchymal stem cells into hepatocyte-like cells. Biochem. Biophys. Res. Commun. 2005; 330[4): 1153-61.Lee K.D., Kuo T.K., Whang-Peng J. et al. In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology 2004; 40[6): 1275-84.Wang Y„ Nan X., Li Y. et al. Induction of umbilical cord blood-derived beta2m-c-Met+ cells into hepatocyte-like cells by coculture with CFSC/HGF cells.Liver Transpl. 2005; 11(6): 635-43.Tang X.P., Yang X., Tan H. et al. Clinical and experimental study on therapeutic effect of umbilical cord blood transplantation on severe viral hepatitis. World J. Gastroenterol. 2003; 9[9):1999-2003.