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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Genes &amp; Cells</journal-id><journal-title-group><journal-title xml:lang="en">Genes &amp; Cells</journal-title><trans-title-group xml:lang="ru"><trans-title>Гены и Клетки</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Genes and Cells</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-1829</issn><issn publication-format="electronic">2500-2562</issn><publisher><publisher-name xml:lang="en">Human Stem Cells Institute</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">122294</article-id><article-id pub-id-type="doi">10.23868/gc122294</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Cell technology</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Новости клеточных технологий</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Directed differentiation of human embryonic stem cells into endoderm</article-title><trans-title-group xml:lang="ru"><trans-title>Направленная дифференцировка эмбриональных стволовых клеток человека в энтодерму</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Deev</surname><given-names>R. V.</given-names></name><name xml:lang="ru"><surname>Деев</surname><given-names>Р. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>redaktor@celltranspl.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution></institution></aff><pub-date date-type="pub" iso-8601-date="2006-01-15" publication-format="electronic"><day>15</day><month>01</month><year>2006</year></pub-date><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>18</fpage><lpage>19</lpage><history><date date-type="received" iso-8601-date="2023-01-16"><day>16</day><month>01</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-01-16"><day>16</day><month>01</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://genescells.ru/2313-1829/article/view/122294">https://genescells.ru/2313-1829/article/view/122294</self-uri><abstract xml:lang="ru"><p/></abstract><trans-abstract xml:lang="en"><p/></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>D'Amour К.А., Agulnick A.D., Eliazer S. et al. 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