Genes & CellsGenes & Cells2313-18292500-2562Human Stem Cells Institute12212810.23868/gc122128Research ArticleThe centenary of cell biology: lessons for the futureRepinV. S.<p>Director</p>info@eco-vector.comA.S. Fridenstein Institute of Cell Technologies and Regenerative Medicine15092007239171601202316012023Copyright © 2007, Eco-Vector2007<p>Summing up the main events, discoveries and scientists within the Cell Biology XX, the following topics are highlighted: 1) The beginning of cell biology and the epoch of vitalism - the impact of J. Loeb, R. Harrison, A. Carrel, T. Morgan and D.H. Wilson; 2) from cell ultrastructure to the concept of cell compartmentalization; 3) the beginning of systemic system biology and bioinformatics; 4) recombinant molecular cell biology; 5) developmental cell biology; 6) cell behavior in vitro and in situ; 7) organ and cell transplantation - the impact into basic cell biology; 8) post-genomic gigabyte cell biology: hurdles and limits for the next round of progress; 9) from molecular biology to modular biology; 10) the leading role of a new mega - international project in the XXI century.</p>[Harrison R.G. Further experiments on the development of peripheral nerves. Am. J. Anat. 1906; 5: 121-31.][Harrison R.G. The outgrowth of the nerve fiber as a mode of protoplasmic movement. J. Exp. Zool. 1910; 9: 787-46.][Landecker H. New times for biology: nerve culture and the advent of cellular life in vitro. Stud. Hist. Phil. Biol. Biomed. Sci. 2002; 33: 667-94.][Fell H.B. Tissue culture and its contribution to biology and medicine. J. Exp. 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