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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Genes &amp; Cells</journal-id><journal-title-group><journal-title xml:lang="en">Genes &amp; Cells</journal-title><trans-title-group xml:lang="ru"><trans-title>Гены и Клетки</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Genes and Cells</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-1829</issn><issn publication-format="electronic">2500-2562</issn><publisher><publisher-name xml:lang="en">Human Stem Cells Institute</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">122128</article-id><article-id pub-id-type="doi">10.23868/gc122128</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Historical articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Исторические статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">The centenary of cell biology: lessons for the future</article-title><trans-title-group xml:lang="ru"><trans-title>Клеточной биологии - 100 лет: уроки на будущее</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Repin</surname><given-names>V. S.</given-names></name><name xml:lang="ru"><surname>Репин</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Director</p></bio><bio xml:lang="ru"><p>директор</p></bio><email>info@eco-vector.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.S. Fridenstein Institute of Cell Technologies and Regenerative Medicine</institution></aff><aff><institution xml:lang="ru">НП Институт клеточных технологий и регенерационной медицины им. А.Я. Фриденштейна</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2007-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2007</year></pub-date><volume>2</volume><issue>3</issue><issue-title xml:lang="ru"/><fpage>9</fpage><lpage>17</lpage><history><date date-type="received" iso-8601-date="2023-01-16"><day>16</day><month>01</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-01-16"><day>16</day><month>01</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2007, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2007, Эко-Вектор</copyright-statement><copyright-year>2007</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://genescells.ru/2313-1829/article/view/122128">https://genescells.ru/2313-1829/article/view/122128</self-uri><abstract xml:lang="en"><p>Summing up the main events, discoveries and scientists within the «Cell Biology XX», the following topics are highlighted: 1) The beginning of cell biology and the epoch of vitalism - the impact of J. Loeb, R. Harrison, A. Carrel, T. Morgan and D.H. Wilson; 2) from cell ultrastructure to the concept of cell compartmentalization; 3) the beginning of systemic system biology and bioinformatics; 4) recombinant molecular cell biology; 5) developmental cell biology; 6) cell behavior in vitro and in situ; 7) organ and cell transplantation - the impact into basic cell biology; 8) post-genomic gigabyte cell biology: hurdles and limits for the next round of progress; 9) from molecular biology to modular biology; 10) the leading role of a new mega - international project in the XXI century.</p></abstract><trans-abstract xml:lang="ru"><p>Подводя итог главных событий, открытий и ученых в пределах «Клеточной биологии XX века», следующие темы выдвинуты на первый план: 1 ) начало клеточной биологии и эпоха витализма, связанные с именами Ж. Леба, 3. Гаррисона, А. Карреля, Т. Моргана и Д.Х. Вильсона; 2) движение от концепции ультраструктуры к идее компартментализации клетки; 3) начало системной биологии и биоинформатики; 4) рекомбинантная молекулярная клеточная биология; 5) клеточная биология развития; 6) поведение клетки in vitro и in vivo; 7) клеточная биология и трансплантация органов; 8) постгеномная клеточная биология: препятствия и пределы для следующих этапов прогресса; 9) от молекулярной биологии до модульной биологии; 10) ведущая роль новых мега-проектов в XXI веке.</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Harrison R.G. Further experiments on the development of peripheral nerves. Am. J. Anat. 1906; 5: 121-31.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Harrison R.G. The outgrowth of the nerve fiber as a mode of protoplasmic movement. J. Exp. Zool. 1910; 9: 787-46.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Landecker H. 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