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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Genes &amp; Cells</journal-id><journal-title-group><journal-title xml:lang="en">Genes &amp; Cells</journal-title><trans-title-group xml:lang="ru"><trans-title>Гены и Клетки</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title>Genes and Cells</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2313-1829</issn><issn publication-format="electronic">2500-2562</issn><publisher><publisher-name xml:lang="en">Human Stem Cells Institute</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">121462</article-id><article-id pub-id-type="doi">10.23868/gc121462</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Stem cell therapy of heart failure: clinical trials, problems and perspectives</article-title><trans-title-group xml:lang="ru"><trans-title>Клеточная терапия сердечной недостаточности: клинический опыт, проблемы и перспективы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochegura</surname><given-names>T N</given-names></name><name xml:lang="ru"><surname>Кочегура</surname><given-names>Т Н</given-names></name></name-alternatives><bio xml:lang="ru"><p>Московский Государственный университет им. МБ. Ломоносова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Efimenko</surname><given-names>A Yu</given-names></name><name xml:lang="ru"><surname>Ефименко</surname><given-names>А Ю</given-names></name></name-alternatives><bio xml:lang="ru"><p>Московский Государственный университет им. МБ. Ломоносова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Akopyan</surname><given-names>Zh A</given-names></name><name xml:lang="ru"><surname>Акопян</surname><given-names>Ж А</given-names></name></name-alternatives><bio xml:lang="ru"><p>Московский Государственный университет им. МБ. Ломоносова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Parfenova</surname><given-names>E E</given-names></name><name xml:lang="ru"><surname>Парфенова</surname><given-names>Е Е</given-names></name></name-alternatives><bio xml:lang="ru"><p>Московский Государственный университет им. МБ. Ломоносова</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Kochegura</surname><given-names>T N</given-names></name><bio xml:lang="en"><p>Lomonosov Moscow State University, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Efimenko</surname><given-names>A Y</given-names></name><bio xml:lang="en"><p>Lomonosov Moscow State University, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>Akopyan</surname><given-names>Zh A</given-names></name><bio xml:lang="en"><p>Lomonosov Moscow State University, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name><surname>V</surname><given-names>EV M</given-names></name><bio xml:lang="en"><p>Lomonosov Moscow State University, Moscow</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en"></institution></aff><aff><institution xml:lang="ru">Московский Государственный университет им. МБ. Ломоносова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Lomonosov Moscow State University, Moscow</institution></aff><aff><institution xml:lang="ru"></institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2010-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2010</year></pub-date><volume>5</volume><issue>2</issue><issue-title xml:lang="en">NO2 (2010)</issue-title><issue-title xml:lang="ru">№2 (2010)</issue-title><fpage>11</fpage><lpage>18</lpage><history><date date-type="received" iso-8601-date="2023-01-11"><day>11</day><month>01</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2010, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2010, Эко-Вектор</copyright-statement><copyright-year>2010</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://genescells.ru/2313-1829/article/view/121462">https://genescells.ru/2313-1829/article/view/121462</self-uri><abstract xml:lang="en"><p>Today cell therapy is considered as a new perspective approach in the treatment of different structural and functional changes in ischemic myocardium. In the present review we analyze last achievements in autologous stem and progenitor cells use for the regeneration of damaged myocardium at postinfarct heart failure, chronic ischemic cardiomyopathy and chronic heart failure.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время клеточная терапия рассматривается как новый перспективный подход в борьбе с различными морфо-функциональными изменениями сердца при ишеми-ческом повреждении. В обзоре анализируются последние достижения в области использования аутогенных мультипо-тентных прогениторных клеток для восстановления функции миокарда при постинфарктной сердечной недостаточности, хронической ишемической кардиомиопатии и хронической сердечной недостаточности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cell therapy</kwd><kwd>autologous stem and progenitor cells</kwd><kwd>myocardial infarction</kwd><kwd>chronic heart failure</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>клеточная терапия</kwd><kwd>аутогенные стволовые и прогениторные клетки</kwd><kwd>инфаркт миокарда</kwd><kwd>сердечная недостаточность</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Беленков Ю.Н., Привалова Е.В., Чекнева И.С. Клеточная терапия в лечении хронической сердечной недостаточности: виды применяемых стволовых клеток, результаты последних клинических исследований. 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