Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute12141810.23868/gc121418ArticlesСтатьиPrimenenie v tkanevoy inzhenerii krupnykh sosudov transplantatov na osnove autogennykh mononuklearnykh kletok kostnogo mozgaПрименение в тканевой инженерии крупных сосудов трансплантатов на основе аутогенных мононуклеарных клеток костного мозгаGrigoryanA SГригорянА С

000 «Транс-Технологии», Санкт-Петербург

KruglyakovP VКругляковП В

000 «Транс-Технологии», Санкт-Петербург

000 «Транс-Технологии», Санкт-Петербург1509200943NO3 (2009)№3 (2009)374111012023Copyright ©; 2009, Eco-VectorCopyright ©; 2009, Эко-Вектор2009Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/121418

В настоящее время эффективность операций по замене пораженных атеросклерозом и стенозированных крупных сосудов аутотрансплантатами, а также операций по ангиопластике, направленных на коррекцию врожденных дефектов сердечнососудистой системы, весьма невелика, и зачастую пациентам требуются повторные операции. В связи с этим необходима разработка искусственных тканеинженерных конструкций, обладающих достаточной прочностью и способных со временем замещаться тканями реципиента, обеспечивая формирование функционального сосуда. Обзор посвящен наиболее успешным доклиническим и клиническим исследованиям по данному направлению.

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