Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute12071210.23868/201808015ArticlesСтатьиResearch ArticleStem (progenitor) thyroid cells and their probable applications in tissue engeniringСтволовые и (или) прогениторные клетки щитовидной железы и возможности их использования в тканевой инженерииSergeevaN. SСергееваН. СHesuaniYu. DХесуаниЮ. ДPoljakovA. PПоляковА. ПMironovV. AМироновВ. АKaprinA. DКапринА. ДP.A. Herzen Moscow Oncology Research Institute - a branch of National Medical Research Center of RadiologyМосковский научно-исследовательский онкологический институт им. П.А. Герцена - филиал Национального медицинского исследовательского центра радиологииN.I. Pirogov Russian National Research Medical UniversityРоссийский национальный исследовательский медицинский Университет им. Н.И. Пирогова3D-bioprinting solutions3D-Биопринтинг Солюшенс15062018132VOL 13, NO2 (2018)ТОМ 13, №2 (2018)222405012023Copyright ©; 2018, Eco-VectorCopyright ©; 2018, Эко-Вектор2018Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/120712

The review presents literature data on embryogenesis, physiological and reparative thyroid gland (TG) regeneration in the postnatal period in terms of substantiating the presence of stem/progenitor cells in its tissue. The data concerning genetic and protein markers of thyroid stem cells, as well as markers of their thyroid differentiation, are systematized. Unresolved problems and perspectives of the use of thyroid stem/progenitor cells in tissue engineering are discussed.

В обзоре представлены данные литературы, касающиеся эмбриогенеза, физиологической и репаративной регенерации щитовидной железы (ЩЖ) в постнатальном периоде в аспекте обоснования наличия в ее тканях стволовых и(или) прогениторных клеток. Систематизированы данные, касающиеся генетических и белковых маркеров стволовых клеток ЩЖ, а также маркеров их тиреодифференцировки. Обсуждаются нерешенные проблемы и перспективы использования стволовых и(или) прогениторных клеток ЩЖ в тканевой инженерии.

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