Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute12056610.23868/gc120566ArticlesСтатьиReview ArticleMethods of gene delivery and perspectives of their application in the gene therapyМЕТОДЫ ДОСТАВКИ ГЕНЕТИЧЕСКОГО МАТЕРИАЛА В КЛЕТКИ И ВОЗМОЖНОСТИ ИХ ПРИМЕНЕНИЯ В ГЕННОЙ ТЕРАПИИApartsinE. KАпарцинЕ. Кeka@niboch.nsc.ruKnauerN. YuКнауэрН. ЮInstitute of Chemical Biology and Fundamental Medicine, the Siberian Branch of the Russian Academy of SciencesФГБНУ «Институт химической биологии и фундаментальной медицины СО РАН»Research Institute of Fundamental and Clinical ImmunologyНаучно-исследовательский институт фундаментальной и клинической иммунологии15062016112VOL 11, NO2 (2016)ТОМ 11, №2 (2016)324105012023Copyright ©; 2016, Eco-VectorCopyright ©; 2016, Эко-Вектор2016Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/120566

Gene therapy is believed to be among the most promising directions of the future medicine. Thus, the development of efficient and safe methods of the nucleic acid delivery to the target cells, tissues and organs ecomes of great current interest. This review summarizes recent data on the approaches for the gene delivery and discusses clinical aspects of the gene therapy.

Генная терапия считается одним их наиболее перспективных направлений медицины будущего. В связи с этим, становится актуальной разработка эффективных и безопасных методов доставки нуклеиновых кислот в клетки-мишени на организменном уровне. В настоящем обзоре систематизированы литературные данные последних лет о способах доставки генетического материала в клетки человека и обсуждаются некоторые клинические аспекты генной терапии.

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