Genes & CellsGenes & CellsГены и КлеткиGenes and Cells2313-18292500-2562Human Stem Cells Institute12055110.23868/gc120551ArticlesСтатьиReview ArticleEncapsulation of cells and tissues of the pancreas: problems and ways of their overcomingИнкапсуляция клеток и тканей поджелудочной железы: проблемы и пути их преодоленияShupletsovaV. VШуплецоваВ. ВLitvinovaL. SЛитвиноваЛ. Сlarisalitvinova@yandex.ruKarpovA. AКарповА. АKorniushynO. VКорнюшинО. ВNeimarkA. EНеймаркА. ЕSohonevichN. AСохоневичН. АVasilenkoM. AВасиленкоМ. АDoraS. VДораС. ВI.Kant Baltic Federal UniversityБалтийский федеральный университет им. И. КантаI.P. Pavlov First Saint Petersburg State Medical UniversityПервый Санкт-Петербургский государственный медицинский университет им. ак. И. П. ПавловаV.A. Almazov Northwestern Federal Medical Research CenterСеверо-Западный федеральный медицинский исследовательский центр им. В.А. АлмазоваITMO UniversityУниверситет ИТМО15032016111VOL 11, NO1 (2016)ТОМ 11, №1 (2016)182305012023Copyright ©; 2016, Eco-VectorCopyright ©; 2016, Эко-Вектор2016Eco-VectorЭко-Векторhttps://genescells.ru/2313-1829/article/view/120551

Despite advances in treatment the patients suffering from diabetes mellitus type 1 have a lifetime shorter the average in population. This is defined primarily by the lack of sufficient glycemic control in these patients The active researches investigating the safety and efficacy of the grafting materials have been carried out in the last decades The review presents modern data on the use of pancreas cells and tissues encapsulation as a possible method for treatment of diabetes type 1 The main problems of the capsules application and possible ways to overcome them were described

Пациенты, страдающие сахарным диабетом 1 типа, несмотря на достигнутые успехи в лечении, имеют продолжительность жизни ниже средней в популяции. Это обусловлено, прежде всего, отсутствием удовлетворительного контроля гликемии у больных диабетом. В последние десятилетия активно ведутся работы по оценке безопасности и эффективности применения различных трансплантационных материалов В обзоре представлены современные представления о применении инкапсуляции клеток и тканей поджелудочной железы как возможного метода лечения сахарного диабета 1 типа. Рассмотрены основные проблемы использования капсул и возможные пути их преодоления

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