Fusion of bone marrow cells with muscle cells is not therapeutically effective


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A. V. Bersenev

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Email: info@eco-vector.com
Russian Federation

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2. Figure. Scheme of possible reprogramming of the nucleus of a defective myocyte by fusion with a donor “normal” cell: I - all mature muscle genes are turned off; II - common (committed) genes are on, mature (specific) - are off; III - “early” muscle genes are turned on, “mature” muscle genes are turned off; IV - all muscle genes are included (according to Cossu G. J Clin Invest 2004; 114: 1542, with changes).

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