Cellular technologies in system of the intensive care of traumatic comas
- Authors: Parljuk О.V.1, Seledtsov V.I.2, Rabinovich S.S.3, Seledtsova G.V.4, Astrakov S.V.1, Jarohno V.I.1, Kozlov V.A.4
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Affiliations:
- 34 Munisipal Clinical Hospital, Novosibirsk
- lmmanuel Kant State University of Russia
- Novosibirsk State Medical University
- Institute of Clinical Immunology, Russian Academy of Medical Sciences
- Issue: Vol 3, No 3 (2008)
- Pages: 51-56
- Section: Clinical experience
- URL: https://genescells.ru/2313-1829/article/view/167250
- ID: 167250
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Abstract
The purpose of the present research is a studying of an opportunity to use cellular technologies in treatment of patients with traumatic comas. Cellular therapy was applied at 38 patients with a serious brain injury. All of them were at entering in clinic in coma I-III of a degree and had attributes of a vegetative condition formation on a background of stable vital functions. Suspension of unripe nervous and hemopoietic cells entered into a subarachnoid space through a spinal puncture. The control group consists of 38 patients and was comparable to group of research. Оutcomes of treatment were appreciated on Karnoffsky scale, Barthel ADL index and also on a scale of outcomes of Glasgow. Favorable (good and satisfactory) outcome of disease was marked at 33 (86,8 %) patients, receiving cellular therapy, and at 15 (39,5%) patients of control group. Good outcomes in control group were not. According to observation 1,5 years, the life quality of patients, receiving cellular therapy, authentically surpassed a similar control parameter. Complications of this method in the nearest and remote period were not registered. Received data specify possible expediency application of cellular therapy at patients with comas in the acute period of a serious brain injury.
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About the authors
О. V. Parljuk
34 Munisipal Clinical Hospital, Novosibirsk
Author for correspondence.
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
V. I. Seledtsov
lmmanuel Kant State University of Russia
Email: bozo.ilya@gmail.com
Russian Federation, Kaliningrad
S. S. Rabinovich
Novosibirsk State Medical University
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
G. V. Seledtsova
Institute of Clinical Immunology, Russian Academy of Medical Sciences
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
S. V. Astrakov
34 Munisipal Clinical Hospital, Novosibirsk
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
V. I. Jarohno
34 Munisipal Clinical Hospital, Novosibirsk
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
V. A. Kozlov
Institute of Clinical Immunology, Russian Academy of Medical Sciences
Email: bozo.ilya@gmail.com
Russian Federation, Novosibirsk
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