Vascular endothelial growth factor in tissues of patients with IHD, before and after coronary bypass surgery

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We present the comparative results of the study of endothelial growth factor (VEGF) in the tissues of patients with and without coronary artery disease. Concentration of the investigated growth factor was found to be higher in tissues of patients with IHD (p<0.05). Identified high content of VEGF in adipose tissue of involutive thymus and epicardial adipose tissue was stable (without signs of decreasing concentration for 3 days). Among the potential sources of VEGF, the fluid aspirated from the drains in patients on 1 day after open myocardial revascularization was proposed. Removal of blood corpuscle from the liquid did not significantly reduce the concentration of VEGF (p>0.05), but decreased the total volume of the liquid by almost 4 times (p<0.05).

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About the authors

Yu. L Shevchenko

N.I. Pirogov National Medical and Surgical Center

G. G Borshchev

N.I. Pirogov National Medical and Surgical Center


V. S Fomina

N.I. Pirogov National Medical and Surgical Center

K. F Kim

N.I. Pirogov National Medical and Surgical Center


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