Pathomorphologic characteristics of venous vessels after the application of different methods of endovascular eliminating of venous reflux - experimental study
- Authors: Abrosimova T.I1, Kurmanskii A.V2, Borisov A.A2
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Affiliations:
- Lomonosov Interdistrict Hospital
- Ryazan State Medical University
- Issue: Vol 15, No 1 (2020)
- Pages: 71-77
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/122064
- DOI: https://doi.org/10.23868/202003010
- ID: 122064
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Abstract
Varicose veins have been the subject of a recent technologies of nontumescent treatment that outline the safety and effectiveness questions concerning proposed obliteration methods. The goal of this study is to analyze changes in the venous wall structure appearing as a result of using thermal tumescent and nonthermal nontumescent methods in compare. Methods: microscopic investigation of vein specimens of adult sheep (n=9) performed on 1, 7 and 100 day after procedure to determine the grade of damage and inflammation. Results: On the 1st and 7th days after the use of endovenous laser, endothelial destruction was 100%, with total depth damage of vein wall and total destruction of the elastic carcass, also traces of carbonization on the first and vaporization on the seventh day have been seen. In a result of the use of nonthermal method, there was a residual endothelium up to 30%; with the use of cyanoacrylate glue - up to 10%. In the long-term period of observation, glue masses undergo a sewage process and is preserved as separate lumps, there is an abundance of multicore macrophages with fragmented glue in the cytoplasm. Conclusion: the results allow us to consider nonthermal nontumescent methods as a possible alternative to thermal methods available in clinical practice.
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About the authors
T. I Abrosimova
Lomonosov Interdistrict Hospital
Email: abrosimova9409@gmail.com
A. V Kurmanskii
Ryazan State Medical University
A. A Borisov
Ryazan State Medical University
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