Endogenous secretion of vascular endothelial growth factor by multipotent mesenchymal stromal cellsderived from human third molar dental follicles

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Human stem cells secretome is currently a very hot area
of research. We report that multipotent mesenchymal stromal
cells isolated from human third molar dental follicles (MMSCTMDF),
are able to secrete high levels of vascular endothelial
growth factor (VEGF) when cultured in vitro. Due to the fact
that VEGF is a well known angiogenic and neuroprotective
factor, the use of MMSC-TMDF is promising for the
development of stem cell therapy of various degenerative
human diseases.

About the authors

V V Solovyeva

Kazan (Volga Region) Federal University, Kazan

Kazan (Volga Region) Federal University, Kazan

N L Blatt

Kazan (Volga Region) Federal University, Kazan

Kazan (Volga Region) Federal University, Kazan

A K Shafigullina

Kazan State Medical University, Kazan

Kazan State Medical University, Kazan

A A Rizvanov

Kazan (Volga Region) Federal University, Kazan

Kazan (Volga Region) Federal University, Kazan


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