Endogenous secretion of vascular endothelial growth factor by multipotent mesenchymal stromal cellsderived from human third molar dental follicles
- Authors: Solovyeva VV1, Blatt NL1, Shafigullina AK2, Rizvanov AA1
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Affiliations:
- Kazan (Volga Region) Federal University, Kazan
- Kazan State Medical University, Kazan
- Issue: Vol 7, No 3 (2012)
- Pages: 155-158
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121668
- DOI: https://doi.org/10.23868/gc121668
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Abstract
Human stem cells secretome is currently a very hot area
of research. We report that multipotent mesenchymal stromal
cells isolated from human third molar dental follicles (MMSCTMDF),
are able to secrete high levels of vascular endothelial
growth factor (VEGF) when cultured in vitro. Due to the fact
that VEGF is a well known angiogenic and neuroprotective
factor, the use of MMSC-TMDF is promising for the
development of stem cell therapy of various degenerative
human diseases.
of research. We report that multipotent mesenchymal stromal
cells isolated from human third molar dental follicles (MMSCTMDF),
are able to secrete high levels of vascular endothelial
growth factor (VEGF) when cultured in vitro. Due to the fact
that VEGF is a well known angiogenic and neuroprotective
factor, the use of MMSC-TMDF is promising for the
development of stem cell therapy of various degenerative
human diseases.
About the authors
V V Solovyeva
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
N L Blatt
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
A K Shafigullina
Kazan State Medical University, KazanKazan State Medical University, Kazan
A A Rizvanov
Kazan (Volga Region) Federal University, KazanKazan (Volga Region) Federal University, Kazan
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