Influence of porous three-dimensional implants from nitinol on culture of multipotent mesenchymal stromal cells
- Authors: Volchkov S.E1, Shishkovsky I.V1,2, Bairikov I.M1
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Affiliations:
- Samara State Medical University, Samara
- P.N. Lebedev Physics Institute of RAS, Samara branch, Samara
- Issue: Vol 8, No 1 (2013)
- Pages: 51-56
- Section: Articles
- URL: https://genescells.ru/2313-1829/article/view/121609
- DOI: https://doi.org/10.23868/gc121609
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Abstract
The results of in vitro studies about biocompatibility of three-dimensional porous implants made of nickel-titanium (nitinol) are presented in this article. The porous scaffolds were created via layer-by layer selective laser sintering method and incubated with cultures of multipotent mesenchymal stromal cells. The microstructures of implants surface were observed by scanning electron and optical microscopy. It was shown that nitinol implants have neither toxicity nor other damage action on cells, but decrease the proliferative activity and migration ability of MMSC.
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About the authors
S. E Volchkov
Samara State Medical University, Samara
I. V Shishkovsky
Samara State Medical University, Samara; P.N. Lebedev Physics Institute of RAS, Samara branch, Samara
I. M Bairikov
Samara State Medical University, Samara
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