Prospects for tissue engineered bile duct

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Intraoperative bile duct injures requiring its repair observed in 0. 05-2. 7% of patients, who underwent cholecystectomy due to cholelithiasis Lots of patients require reconstructive bile duct surgery given that cholecystectomy is the second most common surgery in the abdominal region, and more than 1 mln operations are made all over the world per year. Previously stitching of the crossed bile duct edges was used, but in most cases this entailed the bile duct stricture and disturbance of the bile outflow. At present, the standard surgery includes suturing of the duct with small intestine, but such a reconstruction, in turn, can lead to liver abscess, biliary cirrhosis and increased risk of cholangiocarcinoma. in this review, we consider the possibility of creating fragments of tissue-engineered bile duct that involves the use multilayer tissue-engineered structures consisting of a composite matrix, cells and signaling molecules that stimulate local proliferation and neovascularization.

Full Text

Restricted Access

About the authors

T. G Dyuzheva

Sechenov First Moscow State Medical University

A. V Lyundup

Sechenov First Moscow State Medical University

I. D Klabukov

Sechenov First Moscow State Medical University

Email: ilya.klabukov@gmail.com

S. N Chvalun

National Research Center “Kurchatov Institute"

T. E Grigorev

National Research Center “Kurchatov Institute"

A. D Shepelev

National Research Center “Kurchatov Institute"

T. H Tenchurin

National Research Center “Kurchatov Institute"

M. E Krasheninnikov

Sechenov First Moscow State Medical University

R. V Oganesyan

Sechenov First Moscow State Medical University

References

  1. Гальперин Э.И., Дюжева Т.Г., Чевокин А.Ю. Стриктуры желчных протоков. В: Гальперин Э.И., Ветшева П.С., редакторы. Руководство по хирургии желчных протоков. М.: Видар; 2006. с. 503-22.
  2. Kimura Y., Takada T., Kawarada Y. et al. Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines. J. Hepat. -Bil. -Pancr. Surg 2007; 14(1): 15-26.
  3. Soehendra N., Reynders-Frederix V. Palliative bile duct drainage-a new endoscopic method of introducing a transpapillary drain. Endoscopy 1980; 12(1): 8-11.
  4. Laurence B.H., Cotton P.B. Decompression of malignant biliary obstruction by duodenoscopic intubation of bile duct BMJ 1980; 280(6213): 522-23.
  5. Blero D., Huberty V., Devière J. Novel biliary self-expanding metal stents: indications and applications. Exp. Rev. Gastroenterol. Hepatol. 2015; 9(3): 359-67.
  6. Rey J.F. Dumas R., Canard J.M. et al. Guidelines of the French Society of Digestive Endoscopy: biliary stenting. Endoscopy 2002; 34(2): 169-73.
  7. Jang S.I., Lee D.K. Stents with specialized functions: drug-eluting stents and stents with antireflux devices. Gastrointest. Interv. 2015; 4(1): 50-4.
  8. Aikawa M., Miyazawa M., Okamoto K. et al. A novel treatment for bile duct injury with a tissue-engineered bioabsorbable polymer patch. Surgery 2010; 147(4): 575-80.
  9. Rosen M., Ponsky J., Petras R. Small intestinal submucosa as a bioscaffold for biliary tract regeneration. Surgery 2002; 132: 480-6.
  10. Ellis H., Hoile R.W. Vein patch repair of the common bile duct J. Royal Soc. Med. 1980; 73(9): 635.
  11. Sedgwick C.E. Reconstruction of the common bile duct with a free ureteral graft; an experimental study. Surg. Gynecol. Obstet. 1951; 92: 571-3.
  12. Aydin M., Bakir B., Kösem M. et al. Biliary tract reconstruction with autologous rectus sheath graft--an experimental study Hep -Gastroenterol. 2004; 52(64): 1019-22.
  13. Дюжева Т.Г., Савицкая Е.Е., Котовский А.Е. и соавт. Биодеградируемые материалы и методы тканевой инженерии в хирургии желчных протоков. Анналы хирургической гепатологии 2012; 17(1): 94-9.
  14. Haber G.B., Freeman M.L., Bedford R. et al. A prospective multi-center study of a bioabsorbable biliary wallstent (BAS) in 50 patients with malignant obstructive jaundice (MOJ) Gastrointest Endosc. 2001; 53(5): AB121.
  15. Yamamoto K., Yoshioka T., Furuichi K. et al. Experimental study of poly-L-lactic acid biodegradable stents in normal canine bile ducts Cardiovasc. Intervent. Radiol. 2011; 34: 601-8.
  16. Tao L., Li Q., Ren H. et al. Repair of extrahepatic bile duct defect using a collagen patch in a swine model. Artificial organs 2015; 39(4): 352-60.
  17. Alonso A.J., del Olmo Rivas C., Machado Romero I. et al. Bile duct reconstruction using 3-dimensional collagen tubes. Cirugia Espanola (English Edition) 2013; 91(9): 590-4.
  18. Ismail A., Ramsis R., Sherif A. et al. Use of human amniotic stem cells for common bile duct reconstruction: vascularized support of a free amnion graft. Med. Sci. Monitor Bas. Res. 2009; 15(9): BR243-7
  19. Mills S.E., editor Histology for pathologists 4th Ed Philadelphia: Lippincott Williams & Wilkins; 2012.
  20. Sutton M.E., Dries S., Koster, M.H. et al. Regeneration of human extrahepatic biliary epithelium: the peribiliary glands as progenitor cell compartment. Liver International 2012; 32(4): 554-9
  21. Онищенко Н.А., Люндуп А.В., Газизов И.М. и др. Двухфазная динамика воздействия мезенхимальных мультипотентных стромальных клеток (ММСК) костного мозга на печень при моделировании фиброзирующего гепатита Вестник трансплантологии и искусственных органов 2011; 13(3): 51-8.
  22. Barralet J.E., Wallace L.L., Strain A.J. Tissue engineering of human biliary epithelial cells on polyglycolic acid/polycaprolactone scaffolds maintains long-term phenotypic stability Tissue engineering 2003; 9(5): 1037-45.
  23. Miyazawa M., Torii T., Toshimitsu Y. et al. A tissue-engineered artificial bile duct grown to resemble the native bile duct Am J Transpl. 2005; 5(6): 1541-7.
  24. Zong С., Wang M., Yang F. et al. A novel therapy strategy for bile duct repair using tissue engineering technique: PCL/PLGA bilayered scaffold with hMSCs Journal of tissue engineering and regenerative medicine. 2015; 4(7): 524-31.
  25. Yang J., Cao С., Wang W. et al. Proliferation and osteogenesis of immortalized bone marrow-derived mesenchymal stem cells in porous polylactic glycolic acid scaffolds under perfusion culture J Biomed. Mat. Res. Part A 2010; 92(3): 817-29.

Copyright (c) 2016 Eco-Vector


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: ПИ № ФС 77 - 85657 от 21.07.2023 от 11.03.2014.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies