Recovery options of reproductive function of cancer patients due to transplantation of cryopreserved ovarian tissue



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Abstract

Cancer patients survive at increasing rates, but successful treatment in younger patients often leads to reduced fertility. If damage to reproductive organs from treatment is unavoidable, cryopreservation of ovarian tissue can protect fertility for young patients prior to treatment. Well known that the mammalian ovary contains a huge stock of resting оосуtes. The large store of these small follicles creates a potential source of oocytes for fertilization. To utilize the potential female gametes stored in ovaries, it will be important to safe ovarian tissue before oocytes undergo degeneration during treatment of cancer cryopreservation and transplantation of ovarian tissue are two emerging techniques for fertility preservation, especially in yang cancer patients If these technologies are to become widely accepted, they need to be safe, easy to perform and must obtain favorable result. Recent advances in cryobiology have made it possible to preserve ovarian tissue with relatively little loss of viability. If gonadal toxicity of chemo radiotherapy is unavoidable, physicians also should be knowledgeable about options for fertility preservation and offer patients a referral to a fertility specialist. The ability of having genetically related children is an important issue for patients surviving cancer.

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About the authors

E. V Abakushina

A.F. Tsyb Medical Radiological Research Center - branch of the National Medical Research Radiological Centre; Yamaguchi University

Email: abakushina@mail.ru

T. Otoi

Yamaguchi University

A. D Kaprin

National Medical Research Radiological Centre

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