Features of multipotent mesenchymal stromal cells derived from various intraoral sources



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Abstract

Multipotent mesenchymal stromal cells (MMSC) derived from various intraoral sources attracts attention of an increasing number of researchers due to availability and some features making them different from MMSC of bone marrow or adipose tissue. The review describes the main intraoral sources, characterizes their anatomical, topographical and histological peculiarities which may influence on MMSC morphofunctional profile. In comparative aspect we systematized the principal data concerning properties of MMSC derived from gingiva, buccal mucosa; periodontal ligament, dental pulp, apical papilla, jaw periosteum. It is not possible to compare MMSC of various intraoral sources under some parameters because of absence appropriate experimental findings. Some additional difficulties are caused by contradictions in published materials that are discussed in the review as well.

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About the authors

I. Y Bozo

Human Stem Cells Institute; A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia; A.I. Evdokimov Moscow State University of Medicine and Dentistry

Moscow, Russia

V. L Zorin

Human Stem Cells Institute; A.I. Burnasyan Federal Medical Biophysical Center

Moscow, Russia

I. I Eremin

A.I. Burnasyan Federal Medical Biophysical Center

Moscow, Russia

R. V Deev

Human Stem Cells Institute; Kazan (Volga region) State University

Kazan,Moscow, Russia

A. Y Drobyshev

A.I. Evdokimov Moscow State University of Medicine and Dentistry

Moscow, Russia

I. N Korsakov

A.I. Burnasyan Federal Medical Biophysical Center

Moscow, Russia

AA. A Pulin

A.I. Burnasyan Federal Medical Biophysical Center

Moscow, Russia

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